Paxil During Pregnancy Increases Birth Defects
The popular antidepressants Paxil (Paroxetine) Paxil CR, Pexeva, and generic paroxetine hydrochloride has been linked to increased birth defects, lung damage, heart valve defects, atrial septal defects (ASD), ventricular septal defects (VSD), tetralogy of fallot TOF, transposition of the great arteries, coarctation of the aorta, transposition of the greater vessels, Persistent Pulmonary Hypertension (PPHN), pulmonary stenosis, holes in heart / heart murmur, abnormal cranial shaped heads, bilateral club feet, respiratory pulmonary failure, club foot and other rare birth defects to infants of mothers that were prescribed Paxil during pregnancy.

FDA Alert of Paxil Pregnancy Side Effects
In 2006, the Food & Drug Administration (FDA) published a study that shows infants born to mothers who took selective serotonin reuptake inhibitors (SSRIs) after the 20th week of pregnancy were 6 times more likely to have persistent pulmonary hypertension (PPHN) than infants born to mothers who did not take antidepressants during pregnancy (see SSRI drug names at the bottom of this sheet).
The first study illustrates the potential risk of relapsed depression after stopping antidepressant medication during pregnancy. The authors followed pregnant women who in the past had major depression. During their pregnancy, some of these women were not feeling depressed and stopped taking their antidepressant medicines. Others stayed on their antidepressant medicines while pregnant. The women who stopped their medicine were five times more likely to have a relapse of depression during their pregnancy than were the women who continued to take their antidepressant medicine while pregnant. This study, by Lee Cohen and other authors, was published February 1, 2006 in the Journal of the American Medical Association (JAMA).
Common Paxil (paroxetine) Side Effects
The common Paxil pregnancy side effects that have been linked to increased birth defects include:
-
Dangerous congenital heart defects
-
Atrial or Ventricular septal defects (ASD & VSD)
-
Heart valve defects
-
Neural tube defects (spina bifida)
-
Persistent pulmonary hypertension (PPHN)
-
Hypoplastic left heart syndrome (HLHS)
-
Autism Spectrum Disorder (ASD)
-
Transposition of the great arteries
-
Coarctation of the aorta
-
Tetralogy of Fallot (TOF)
-
Pulmonary stenosis
-
Abdominal wall defects (gastroschisis & omphalocele
-
Cranial & skull defects (craniosynostosis)
-
Heart Valve Damage
-
Atrial Septal Heart Defects ASD
-
Ventricular Septal Heart Defect VSD
-
Persistent Pulmonary Hypertension (PPHN)
- Bi-Lateral Club Feet and Club Foot